NCT07467941

Impact of Visceral Adiposity on Postoperative Atrial Fibrillation After CABG

Impact of Visceral Adiposity on Postoperative Atrial Fibrillation After Coronary Artery Bypass Grafting (CABG): A Prospective Observational Study

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 300 (estimated)
• Sponsor: Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Obesity has become a major public health problem in both developed and developing countries, with a continuous increase particularly since the 1980s. Moreover, it is a well-established metabolic risk factor for diabetes mellitus, hypertension, and various types of cancer, as well as cardiovascular diseases such as heart failure and coronary artery disease. Body mass index (BMI) is calculated by dividing body weight in kilograms by the square of height in meters and is widely used as an indicator of obesity. However, BMI does not quantitatively reflect body fat distribution and fails to account for components such as skeletal muscle and bone mass. Therefore, interest in assessing body fat distribution has increased, and in recent years, studies evaluating the correlation between anthropometric, biochemical, and anatomical measurements and clinical outcomes have become more frequent. In particular, it is acknowledged that abdominal obesity cannot be accurately represented by BMI alone and is primarily associated with visceral adipose tissue (VAT). The aim of this study is to evaluate the association between preoperative visceral and subcutaneous adipose tissue measurements (VAT and SAT), assessed by ultrasonography in patients scheduled for open-heart surgery, and the development of postoperative atrial fibrillation.

Conditions

• CABG
• Visceral Adipose Tissue
• Atrial Fibrillation (AF)

Interventions

Type	Name	Description
OTHER	Postoperative AF Group	In patients undergoing coronary artery bypass graft surgery, ultrasound-guided measurements of visceral and subcutaneous adipose tissue will be performed preoperatively. The relationship between adipose tissue thickness and the development of postoperative atrial fibrillation will be evaluated by comparing patients who develop AF with those who do not.
OTHER	Non-AF Group	In patients undergoing coronary artery bypass graft surgery, ultrasound-guided measurements of visceral and subcutaneous adipose tissue will be performed preoperatively. The relationship between adipose tissue thickness and the development of postoperative atrial fibrillation will be evaluated by comparing patients who develop AF with those who do not.

Timeline

• Start date: 2026-04-01
• Primary completion: 2026-12-22
• Completion: 2027-01-22
• First posted: 2026-03-12
• Last updated: 2026-03-12