NCT07465406

Postoperative Pain Will be Compared in Cholecystectomy Patients: Half Receiving TAP Block and Half Without it.

Comparison Of Patients Post Operative Pain Undergoing Laparoscopic Cholecystectomy Receiving Tap Block Vs Not Receiving Tap Block

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Darul Sehat Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

This study compares the effectiveness of a Transversus Abdominis Plane (TAP) block in reducing post-operative pain for patients undergoing laparoscopic cholecystectomy. Sixty patients were divided into two groups: one group received a TAP block with a local anesthetic at the end of surgery, and the control group did not. The main goal was to see if the TAP block significantly lowers pain scores (measured on a scale of 0 to 10) within the first 12 hours after surgery and if it reduces the need for additional pain-relief medications.

Detailed description

Laparoscopic cholecystectomy is the gold standard for treating symptomatic cholelithiasis; however, patients often experience significant in the early post-operative period. This randomized controlled trial (RCT) was conducted at the Department of Surgery, Liaquat College of Medicine \& Dentistry, Karachi, to evaluate the analgesic efficacy of the TAP block. A total of 60 patients, aged 18-60 years with ASA I or II, were randomized into two equal groups (n=30 each). The intervention group received an TAP block while the control group received standard post-operative analgesia. The primary objective was to compare the mean Visual Analog Scale (VAS) score at 12 hours post-operation. Secondary objectives included assessing the time to the first request for rescue analgesia and the type of analgesic drug used. Data were analyzed to determine if the TAP block provides superior pain control compared to conventional methods.

Conditions

• Cholelithiasis
• Pain, Postoperative

Interventions

Type	Name	Description
DRUG	Bupivacaine 0.25%	Transversus Abdominis Plane (TAP) block administered by injecting 20ml of 0.25% Bupivacaine between the internal oblique and transversus abdominis muscles.
OTHER	Standard Post-Operative Care	Patients received the routine post-operative analgesia protocol of the hospital (e.g., IV Ketorolac or Paracetamol) without the administration of a TAP block

Timeline

• Start date: 2025-03-11
• Primary completion: 2025-08-11
• Completion: 2025-08-11
• First posted: 2026-03-11
• Last updated: 2026-03-13

Locations

1 site across 1 country: Pakistan