NCT07464730

Postoperative High-flow Nasal Oxygenation After High-risk Surgery in the Frail Adult

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Region Stockholm · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

High flow nasal oxygen (HFNO) in the immediate postoperative period has been demonstrated to reduce the risk of postoperative pulmonary complications (PPC) after cardiothoracic surgery. In specific groups of patients such as the obese and after upper abdominal surgery the results are contradictive. However, there is lack of evidence if HFNO in the general high-risk patient after abdominal and non-cardiac thoracic surgery can reduce the prevalence of PPC, hypoxaemia and escalation of therapy. Therefore, the investigators aim to compare the use of HFNO with conventional oxygen therapy (COT) in high-risk patients after abdominal and non-cardiac thoracic surgery regarding postoperative pulmonary complications.

Conditions

• Postoperative Pulmonary Complications (PPCs)

Interventions

Type	Name	Description
COMBINATION_PRODUCT	High Flow Oxygen	High flow nasal oxygen will be administered in the intervention group
COMBINATION_PRODUCT	Oxygen	Oxygen delivered by nasal cannula or oxymask

Timeline

• Start date: 2026-03-09
• Primary completion: 2028-03-09
• Completion: 2029-03-09
• First posted: 2026-03-11
• Last updated: 2026-03-11

Locations

1 site across 1 country: Sweden