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RecruitingNCT07463586

Cerebral Oxygen Consumption Response to Increased Oxygen Supply and Postoperative Delirium in Older Surgical Patients

Association Between Cerebral Oxygen Consumption Responsiveness to Increased Oxygen Supply and Postoperative Delirium: A Prospective Observational Study Using Functional Near-Infrared Spectroscopy

Status
Recruiting
Phase
Study type
Observational
Enrollment
80 (estimated)
Sponsor
Seoul National University Bundang Hospital · Academic / Other
Sex
All
Age
65 Years
Healthy volunteers

Summary

The goal of this observational study is to learn whether the brain's ability to use oxygen during surgery is associated with postoperative delirium in adults aged 65 years and older undergoing general anesthesia. The main question it aims to answer is: \- Does reduced cerebral oxygen consumption responsiveness during surgery increase the risk of postoperative delirium in older patients? Participants who are undergoing elective laparoscopic surgery under general anesthesia as part of their routine medical care will have brain oxygen levels measured during surgery using a non-invasive forehead sensor, and will be assessed for delirium for up to three days after surgery.

Conditions

Interventions

TypeNameDescription
OTHERIntraoperative Cerebral Oxygen Utilization AssessmentCerebral oxygenation will be monitored intraoperatively using a non-invasive forehead sensor based on functional near-infrared spectroscopy technology. During general anesthesia, the fraction of inspired oxygen (FiO₂) may be temporarily adjusted within the standard clinical range used in routine anesthesia care to evaluate the brain's oxygen utilization response. No experimental oxygen levels or additional therapeutic interventions will be administered beyond standard clinical practice.

Timeline

Start date
2026-03-11
Primary completion
2028-03-01
Completion
2028-05-01
First posted
2026-03-11
Last updated
2026-04-02

Locations

1 site across 1 country: South Korea

Source: ClinicalTrials.gov record NCT07463586. Inclusion in this directory is not an endorsement.