NCT07462533

Assess Efficacy of a Nanodiamond Periprocedural Skin Care Regimen for Ablative Resurfacing

A Prospective, Randomized, Open-label Study Evaluating the Efficacy of a Nanodiamond Periprocedural Skin Care Regimen for Ablative Resurfacing

• Status: Not Yet Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 8 (estimated)
• Sponsor: Goldman, Butterwick, Fitzpatrick and Groff · Academic / Other
• Sex: All
• Age: 35 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The primary objective of this study is to evaluate the efficacy and tolerability of Pavise Extracellular Matrix Restore (ECMR), compared with standard acute post-operative care, when used as the primary occlusive treatment immediately following ablative CO₂ and Er:YAG facial laser resurfacing to support wound healing.

Detailed description

8 patients total will receive an ablative CO₂ and Er:YAG facial laser resurfacing treatment to the face. Each will be assigned to either Group A Control or Group B Active and given a skincare regimen to follow post procedure. Patients will return for follow up visits at Day 1 post procedure, Day 4 post procedure, Day 7 post procedure, 14 days post procedure and 3 months post procedure for 2D photography and assessments.

Conditions

• Skin Laxity

Interventions

Type	Name	Description
DRUG	Pavise Serum	Pavise ECMR (extracellular matrix restore) serum regimen combined with laser treatment
DRUG	Sham Comparator	Vehicle serum regimen combined with laser treatment
DEVICE	Co2/Er:YAG	Ablative laser resurfacing treatment

Timeline

• Start date: 2026-03-20
• Primary completion: 2026-07-30
• Completion: 2026-08-30
• First posted: 2026-03-10
• Last updated: 2026-03-10