Trials / Recruiting
RecruitingNCT07457736
Evaluation of [18F]GATT-44 for Positron Emission Tomography Imaging of the GABA Transporter-1
- Status
- Recruiting
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 32 (estimated)
- Sponsor
- Yale University · Academic / Other
- Sex
- All
- Age
- 18 Years – 60 Years
- Healthy volunteers
- Accepted
Summary
Evaluate \[18F\]GATT-44 (aka \[18F\]GAT44), to characterize its pharmacokinetic, metabolic, and in vivo binding profile, and assess the reproducibility of kinetic and binding parameters. Assess specific binding levels of \[18F\]GATT-44 by conducting a test-block study in humans. Estimate human dosimetry of \[18F\]GATT-44 by performing whole-body imaging studies.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | [ 18F]GATT-44 | First in human radiotracer being evaluated in this study. |
Timeline
- Start date
- 2026-04-01
- Primary completion
- 2030-01-01
- Completion
- 2030-01-01
- First posted
- 2026-03-09
- Last updated
- 2026-04-06
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT07457736. Inclusion in this directory is not an endorsement.