NCT07452588

Effect of Sodium Chloride 5% Solution as an Adjuvant Treatment With Antimicrobial Therapy in the Treatment of Bacterial Infectious Keratitis

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Sohag University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

This study aims to detect the effect of sodium chloride 5% solution as an adjuvant treatment with antimicrobial therapy in treatment of bacterial infectious keratits and to assess whether NaCl 5% accelerates epithelial healing, improves microbial eradication, and enhances visual outcomes in bacterial infectious keratitis.

Detailed description

Prospective randomized control study to detect the effect of sodium chloride 5% solution as an adjuvant treatment with antimicrobial therapy in treatment of bacterial infectious keratits and to assess whether NaCl 5% accelerates epithelial healing, improves microbial eradication, and enhances visual outcomes in bacterial infectious keratitis.Data study will include two groups classified as follow : the first group will include treatment of microbial keratitis by antibiotic with sodium chloride 5% , the second group will include treatment by antibiotic only

Conditions

• Infectious Keratitis
• Adjuvant Treatment Bacterial Infectious Keratitis
• Sodium Chloride 5% Solution

Interventions

Type	Name	Description
DRUG	Sodium chloride 5% solution	Use Sodium chloride 5% solution with usual anti microbial drugs
DRUG	quinolones	Use of usual topical anti microbial treatment only

Timeline

• Start date: 2026-02-01
• Primary completion: 2026-08-01
• Completion: 2027-02-01
• First posted: 2026-03-05
• Last updated: 2026-03-05