NCT07451080

Impact of Anterior Clinoid Process Pneumatization on Optic Canal and Retinal Nerve Fiber Layer

Evaluation of the Effects of Anterior Clinoid Process Pneumatization on Optic Canal Morphometry and Retinal Nerve Fiber Layer Thickness Using Computed Tomography and Optical Coherence Tomography: A Retrospective Cohort Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 100 (actual)
• Sponsor: Elazıg Fethi Sekin Sehir Hastanesi · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This retrospective cohort study aims to evaluate the potential effects of anterior clinoid process (ACP) pneumatization on optic canal morphometry and retinal nerve fiber layer (RNFL) thickness. ACP pneumatization is an anatomical variation that may alter the morphology of the optic canal and potentially influence the optic nerve. Patients aged 18-65 years with available head and neck computed tomography (CT) imaging and optical coherence tomography (OCT) examinations between August 2018 and July 2025 will be retrospectively reviewed. Optic canal length and diameter will be measured using CT images, and RNFL thickness parameters will be obtained from OCT records. Measurements will be compared between patients with and without ACP pneumatization.

Conditions

• Anterior Clinoid Process Pneumatization
• Optic Canal Morphometry
• Retinal Nerve Fiber Layer Thickness

Timeline

• Start date: 2025-08-01
• Primary completion: 2026-01-25
• Completion: 2026-02-01
• First posted: 2026-03-05
• Last updated: 2026-03-05

Locations

1 site across 1 country: Turkey (Türkiye)