Clinical Trials Directory

Trials / Recruiting

RecruitingNCT07449936

COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME

A Phase 3, Multicenter, Prospective, Randomized, Double-Masked, Parallel-Group Study of EYP-1901, a Tyrosine Kinase Inhibitor (TKI), Compared to Aflibercept (2 mg) in Participants With Diabetic Macular Edema (DME)

Status
Recruiting
Phase
Phase 3
Study type
Interventional
Enrollment
240 (estimated)
Sponsor
EyePoint Pharmaceuticals, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a phase 3 randomized, double -masked study comparing the efficacy of EYP-1901 against Aflibercept.

Conditions

Interventions

TypeNameDescription
DRUGEYP-1901Intravitreal Injection
DRUGAflibercept (2.0 mg)Intravitreal Injection

Timeline

Start date
2026-02-16
Primary completion
2027-10-01
Completion
2028-10-01
First posted
2026-03-04
Last updated
2026-04-07

Locations

39 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT07449936. Inclusion in this directory is not an endorsement.