NCT07449806

Assessment of Labial Plate Thickness After Immediate Implant Placement Using Two Different Xenografts in the Esthetic Zone

Assessment of Labial Plate Thickness After Immediate Implant Placement in Type II Extraction Sockets Using Two Different Xenografts in the Esthetic Zone: a Randomized Controlled Clinical Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 26 (estimated)
• Sponsor: Basma Gamal Mohamed Ahmed · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

This randomized clinical trial aims to evaluate labial bone plate changes following immediate implant placement in Type II extraction sockets using two different xenograft materials and de-epithelialized free gingival graft in the esthetic zone . Patients requiring extraction and immediate implant placement will be randomly allocated into two groups according to the xenograft material used for defect grafting. Clinical and radiographic outcomes will be assessed to determine dimensional bone changes and implant success

Detailed description

Immediate implant placement in the esthetic zone has become a predictable treatment modality aiming to reduce treatment time while preserving alveolar bone and soft tissue architecture. However, dimensional alterations of the labial bone plate remain a clinical concern, particularly in Type II extraction sockets. The present randomized controlled clinical trial will compare the effect of two different xenograft materials and de-epithelialized free gingival graft used for defect grafting during immediate implant placement. Eligible patients indicated for tooth extraction and immediate implant placement will be randomly assigned into two parallel groups based on the grafting material used. Clinical evaluation and standardized radiographic assessment using CBCT will be performed to measure labial plate thickness changes, peri-implant bone stability, and implant success outcomes over a defined follow-up period. The findings of this study aim to provide clinical evidence regarding the most effective xenograft material for preserving peri-implant hard tissue contours in the esthetic zone

Conditions

• Alveolar Bone Loss
• Tooth Extraction Status Nos
• Immediate Implant Placement

Interventions

Type	Name	Description
PROCEDURE	Immediate Implant Placement with Medpark S1 xenograft	Immediate implant placement in Type II extraction sockets, with gap grafting using Medpark S1 xenograft .
PROCEDURE	Immediate Implant Placement with bio-Oss xenograft	Immediate implant placement in Type II extraction sockets, with gap grafting using bio-Oss xenograft

Timeline

• Start date: 2025-09-05
• Primary completion: 2026-05-05
• Completion: 2026-09-25
• First posted: 2026-03-04
• Last updated: 2026-03-06

Locations

1 site across 1 country: Egypt