Trials / Enrolling By Invitation
Enrolling By InvitationNCT07448753
ACTG2/FLNA Testing Yield in Adult Idiopathic Chronic Intestinal Pseudo-Obstruction (CIPO) With Reduced/Absent Distal Esophageal Contractility
Diagnostic Yield of ACTG2 and FLNA Gene Assessment in Adult Patients With Idiopathic Chronic Intestinal Pseudo-Obstruction and Reduced or Absent Distal Esophageal Contractility
- Status
- Enrolling By Invitation
- Phase
- —
- Study type
- Observational
- Enrollment
- 20 (estimated)
- Sponsor
- Marina Coletta · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
To assess the diagnostic yield of Sanger sequencing for ACTG2 and FLNA genes evaluation on blood or saliva sample in patients with idiopathic CIPO in which high-resolution esophageal manometry (HRM) shows reduced (DCI \<450 mmHg\*s\*cm) or absent distal esophageal contractility.
Conditions
Timeline
- Start date
- 2025-09-17
- Primary completion
- 2026-09-30
- Completion
- 2027-01-30
- First posted
- 2026-03-04
- Last updated
- 2026-03-05
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT07448753. Inclusion in this directory is not an endorsement.