NCT07448467

Investigation of the Effectiveness of Progressive Resistance Exercise Training in the Management of Lymphedema.

Investigating the Effectiveness of Progressive Resistance Exercise Training in the Management of Lymphedema Developing After Breast Cancer Treatment: a Randomized Controlled Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Uskudar University · Academic / Other
• Sex: Female
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

This study aims to investigate the effect of progressive resistance exercise training on the clinical findings and functional outcomes of lymphedema in individuals who develop upper extremity lymphedema after breast cancer treatment (surgery, chemotherapy and/or radiotherapy).

Detailed description

The study is designed as a randomized controlled trial. Volunteers participating in the study will consist of individuals who have developed lymphedema after breast cancer and who agree to participate in the study. Volunteer female participants will be divided into 2 groups of equal numbers. Participants in the control group will receive lymphedema treatment, while participants in the exercise group will perform progressive resistance upper extremity exercises at home, 2 days a week for 12 weeks. All exercises will be performed with compression bandages. All participants will be evaluated before and after treatment using a hand dynamometer, the Disabilities of the Arm, Shoulder and Hand Scale, and the Lymphedema Quality of Life Questionnaire-Arm.

Conditions

• Lymphedema
• Breast Cancer

Interventions

Type	Name	Description
OTHER	control	Classic lymphedema physiotherapy will be applied.
OTHER	exercise	In addition to classic lymphedema physiotherapy, a progressive resistance exercise training program will be implemented.

Timeline

• Start date: 2026-03-06
• Primary completion: 2026-06-30
• Completion: 2026-08-30
• First posted: 2026-03-04
• Last updated: 2026-03-12

Locations

1 site across 1 country: Turkey (Türkiye)