NCT07446634

Maxillomandibular Advancement Surgery for Treatment of Obstructive Sleep Apnoea Syndrome

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 48 (estimated)
• Sponsor: Jani Talvilahti · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This study looks at how jaw surgery called maxillomandibular advancement with counterclockwise rotation affects breathing during sleep in people with moderate to severe obstructive sleep apnea who cannot tolerate standard treatments such as Continous Positive Airway pressure treatment. The participants are followed over time to see whether the surgery improves sleep apnea symptoms, daytime sleepiness, and airway size, and whether these improvements last. Advanced three-dimensional imaging and airflow analysis are used to better understand how the surgery changes the airway and breathing. The goal is to evaluate the long-term effectiveness and safety of this surgical treatment.

Conditions

• Sleep Apnea, Obstructive

Interventions

Type	Name	Description
PROCEDURE	Maxillomandibular advancement surgery with counterclockwise rotation	Maxillary advancement by LeFort I osteotomy and mandibular advancement by bilateral sagittal split osteotomy

Timeline

• Start date: 2014-02-06
• Primary completion: 2031-06-30
• Completion: 2032-06-30
• First posted: 2026-03-03
• Last updated: 2026-03-03

Locations

1 site across 1 country: Sweden