Clinical Trials Directory

Trials / Not Yet Recruiting

Not Yet RecruitingNCT07445906

A Study of RG002C0106 Injection in Adult Participants With Normal Renal Function and Mild-to-Moderate Renal Impairment

A Phase I Clinical Study to Evaluate the Safety, Tolerability, PK and PD of RG002C0106 Injection in Adult Participants With Normal Renal Function and Mild-to-Moderate Renal Impairment

Status
Not Yet Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
24 (estimated)
Sponsor
Rigerna Therapeutics Co., Ltd.; Rigerna Therapeutics (Beijing) Co., Ltd. · Industry
Sex
All
Age
18 Years – 60 Years
Healthy volunteers
Accepted

Summary

This is a Phase I trial designed to evaluate the impact of renal impairment on the efficacy and safety of the drug by comparing pharmacokinetic (PK) parameters and pharmacodynamic (PD) markers after a single subcutaneous injection of RG002C0106 between trial participants with normal renal function and those with mild to moderate renal impairment.

Conditions

Interventions

TypeNameDescription
DRUGRG002C0106Subcutaneous (SC) single dose 200mg

Timeline

Start date
2026-03-15
Primary completion
2026-12-01
Completion
2026-12-01
First posted
2026-03-03
Last updated
2026-03-03

Source: ClinicalTrials.gov record NCT07445906. Inclusion in this directory is not an endorsement.