NCT07445607

"Mulligan Technique vs Phonophoresis With Chitosan for Patellofemoral Pain"

Mulligan Technique Vs Phonophoresis With Chitosan Gel on Neuromuscular Control in Patellofemoral Pain Syndrome

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 45 (estimated)
• Sponsor: Ahram Canadian University · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Not accepted

Summary

Patellofemoral pain syndrome (PFPS) is a common knee condition causing pain and dysfunction. This study aims to compare the effectiveness of two physical therapy treatments for PFPS: Mulligan mobilization with movement technique versus phonophoresis with chitosan gel. Forty-five participants with patellofemoral pain syndrome will be randomly assigned to one of three groups: (1) Mulligan technique group, (2) Phonophoresis with chitosan gel group, or (3) Control group receiving standard physical therapy exercises. Each group will receive treatment 3 times per week for 4 weeks. The researchers want to determine which treatment is more effective in improving neuromuscular control, reducing pain, and improving function in patients with patellofemoral pain syndrome. Participants will be assessed before and after the treatment period. This study may help physical therapists and healthcare providers choose the most effective treatment approach for patients with patellofemoral pain.

Conditions

• Patellofemoral Pain Syndrome

Interventions

Type	Name	Description
PROCEDURE	Mulligan technique	Each mobilization with movement (MWM) is performed in three sets of 10 repetitions, with a 30-second rest interval between sets, 3 times per week for 6 weeks, before hip and knee strengthening exercises.
PROCEDURE	Phonophoresis with Chitosan Gel	Phonophoresis (ultrasound with chitosan gel) is applied at 1 MHz, 1.0 W/cm², continuous mode, for 5 minutes, 3 times per week for 6 weeks before hip and knee exercises.
BEHAVIORAL	Standard Physical Therapy Exercise Program	Participants attend 3 sessions per week for 6 weeks. Each session includes stretching and hip and knee focused exercises. Progression involves weekly increases in repetitions and resistance based on pain levels (less than 3/10).

Timeline

• Start date: 2026-02-15
• Primary completion: 2026-07-01
• Completion: 2026-08-01
• First posted: 2026-03-03
• Last updated: 2026-03-03

Locations

1 site across 1 country: Egypt