NCT07443982

Acute Myocardial Infarction - Allied Health-Oriented Patient-centered Digitally-Enabled Care

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,633 (actual)
• Sponsor: National University Heart Centre, Singapore · Academic / Other
• Sex: All
• Age: 21 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The Acute Myocardial Infarction - allied Health Oriented, Patient centered, and digitally Enabled care (AMI-HOPE) program is a model of care designed to improve post-AMI well-being, safety, and outcomes through greater involvement of AHPs in patient care and integrating digital technologies into routine primary care disease management. AMI-HOPE aims to deliver solutions to these identified gaps of care which will transform healthcare planning both at cluster and national levels. The cornerstone of the AMI-HOPE program will be upskilling pharmacists to take on low-intermediate complexity clinician roles during the post-discharge period. The first 6 months will be anchored by tertiary care before a handoff to primary care. This frees up cardiologists to focus on high complexity cases.

Detailed description

The AMI-HOPE program addresses three critical healthcare challenges: insufficient specialist capacity, limited outpatient clinic infrastructure, and excessive dependence on hospital-based rather than community-based care during the vulnerable early post-discharge period for myocardial infarction patients. The program trains pharmacists to provide comprehensive post-MI (Myocardial Infarction) care through personalized cardiovascular medication optimization, targeted interventions for patients with reduced ejection fraction, smoking cessation support, and lifestyle counseling covering diet and exercise. Care delivery occurs remotely through integrated digital health platforms that facilitate continuous vital signs monitoring, deliver structured patient education at strategic intervals, and promote effective self-management capabilities. This proof-of-value stepped-wedge pragmatic trial that evaluates the effectiveness of the AMI-HOPE intervention is conducted across seven hospitals and eighteen primary care polyclinics spanning Singapore's three health clusters.

Conditions

• Acute Myocardial Infarction (AMI)

Interventions

Type	Name	Description
OTHER	Standard of Care (SOC)	Standard of care treatment without the pharmacist-led digital platform assisted care
OTHER	Pharmacist-led digital platform assisted care	Up titration of medications by pharmacist. AMI-HOPE centers around a digital platform that offers continuous telemonitoring on patients' vitals, tailored medication prescription with support from pharmacists and personalised lifestyle nudges and educational material.

Timeline

• Start date: 2023-01-11
• Primary completion: 2026-09-30
• Completion: 2026-09-30
• First posted: 2026-03-02
• Last updated: 2026-03-02

Locations

6 sites across 1 country: Singapore