NCT07443059

A Study of Zovaglutide (ZT002 Injection) in Participants With Impaired Kidney Function and Healthy Participants

A Phase I Clinical Study to Evaluate the Pharmacokinetic Characteristics and Safety of Single-dose of Zovaglutide (ZT002 Injection) in Participants With Different Degrees of Renal Insufficiency and Matched Participants With Normal Renal Function

• Status: Not Yet Recruiting
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Beijing QL Biopharmaceutical Co.,Ltd · Industry
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

This study is a single-dose, open-label, parallel design phase I clinical study to evaluate the PK characteristics and safety of single subcutaneous injection of ZT002 Injection in participants with different degrees of renal insufficiency and matched participants with normal renal function.

Conditions

• Overweight , Obesity

Interventions

Type	Name	Description
DRUG	Zovaglutide	Receive a single dose , SC
DRUG	Zovaglutide	Receive a single dose , SC
DRUG	Zovaglutide	Receive a single dose , SC
DRUG	Zovaglutide	Receive a single dose , SC

Timeline

• Start date: 2026-04-10
• Primary completion: 2026-12-03
• Completion: 2027-03-19
• First posted: 2026-03-02
• Last updated: 2026-03-02

Locations

3 sites across 1 country: China