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Not Yet RecruitingNCT07441486

A Single-arm, Prospective, Phase II Clinical Study of the Combination of Entinostat and Oral Paclitaxel in the Treatment of HR+HER2- Advanced Breast Cancer

Status
Not Yet Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
50 (estimated)
Sponsor
Tianjin Medical University Cancer Institute and Hospital · Academic / Other
Sex
Female
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

Objective: To explore the curative effect and safty of Changchun Ruibin metronomic chemotherapy combined with endistat in the treatment of HR positive HER2 negative advanced breast carcinoma.

Conditions

Interventions

TypeNameDescription
DRUGEntinostatEntinostat will be administered according to the study protocol.
DRUGOral PaclitaxelOral paclitaxel will be administered according to the study protocol.

Timeline

Start date
2026-04-01
Primary completion
2026-04-10
Completion
2026-08-30
First posted
2026-03-02
Last updated
2026-03-02

Source: ClinicalTrials.gov record NCT07441486. Inclusion in this directory is not an endorsement.

A Single-arm, Prospective, Phase II Clinical Study of the Combination of Entinostat and Oral Paclitaxel in the Treatment (NCT07441486) · Clinical Trials Directory