Clinical Trials Directory

Trials / Completed

CompletedNCT07440888

The Factors Influencing the Success of Redo Surgery and Anal Function for Anastomosis Failure or Local Tumor Recurrence

A Multicenter Retrospective Study in China: the Factors Influencing the Success of Redo Surgery and Anal Function for Anastomosis Failure or Local Tumor Recurrence

Status
Completed
Phase
Study type
Observational
Enrollment
143 (actual)
Sponsor
Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

To analyze the influencing factors of the success of redo surgery due to anastomotic fistula or anastomotic recurrence after rectal cancer surgery and to evaluate the anal function of patients

Detailed description

Redo surgery is a critical salvage strategy for anastomotic complications or local recurrence following rectal cancer resection. Despite technical feasibility, functional outcomes remain suboptimal. This study evaluated intestinal continuity restoration and anal function recovery after redo surgery, alongside prognostic factors influencing outcomes. A retrospective multicenter study analyzed 143 patients undergoing redo surgery (2015-2023) for anastomotic failure or local recurrence. Primary endpoints included anatomical restoration of intestinal continuity, while secondary endpoints assessed functional outcomes using the LARS score.

Conditions

Interventions

TypeNameDescription
PROCEDUREredo surgery

Timeline

Start date
2006-03-01
Primary completion
2023-03-01
Completion
2023-12-31
First posted
2026-02-27
Last updated
2026-02-27

Source: ClinicalTrials.gov record NCT07440888. Inclusion in this directory is not an endorsement.