Clinical Trials Directory

Trials / Recruiting

RecruitingNCT07439796

A Study of ORN252 in Healthy Participants

A Phase 1 Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ORN252 in Healthy Participants

Status
Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
20 (estimated)
Sponsor
Orna Therapeutics, Inc. · Industry
Sex
All
Age
18 Years – 55 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to assess the safety and tolerability of ORN252 in healthy adult participants.

Conditions

Interventions

TypeNameDescription
BIOLOGICALORN252ORN252 is a lipid nanoparticle encapsulating a circular RNA encoding an anti-CD19 CAR protein.

Timeline

Start date
2026-03-16
Primary completion
2026-12-01
Completion
2027-03-01
First posted
2026-02-27
Last updated
2026-04-16

Locations

1 site across 1 country: Australia

Source: ClinicalTrials.gov record NCT07439796. Inclusion in this directory is not an endorsement.

A Study of ORN252 in Healthy Participants (NCT07439796) · Clinical Trials Directory