NCT07438717

Comparative Effects of MIIT With CT In Post-MVR Surgery Patients

Comparative Effects Of Moderate Intensity Interval Training With Continuous Training On Physical Capacity, Pulmonary Functions, Cardiac Efficiency And Quality Of Life In Post Mitral Valve Replacement Surgery Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 56 (actual)
• Sponsor: Riphah International University · Academic / Other
• Sex: All
• Age: 40 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Mitral Valve Replacement (MVR) surgery is commonly performed to treat patients with severe mitral valve diseases, such as mitral stenosis or regurgitation. Patients after mitral valve replacement surgery often experience muscular weakness ,fatigue and reduced functional capacity due to the surgical procedure and the time period of post-operative recovery. A structured exercise program helps rebuild strength and regain mobility, allowing patients to perform daily activities with greater ease and independence. Moderate-intensity interval training (MIIT) with continuous training is crucial for patients after mitral valve replacement (MVR) surgery, as it significantly enhances cardiopulmonary fitness. But the comparative effects of Moderate-intensity interval training (MIIT) with continuous training have not been well documented and practiced in Pakistan. The study aims to determine the comparative effects of Moderate-intensity interval training (MIIT) and moderate continuous training on physical capacity, cardiac efficiency, pulmonary function, and quality of life after mitral valve surgery. The study will be single blinded, randomized clinical trial. Based on inclusion and exclusion criteria patients were divided into two groups. The MIIT group and MICT group. The study was of 12 weeks session, 3 sessions per week (3 months). The data was analyzed through SPSS-23. Outcome measures were pulmonary function tests (spirometery), 6-Minute Walk Test (6MWT) and quality of life assessed through IPAQ. Cardiac efficiencywas measured by evaluating heart rate recovery, exercise tolerance, and cardiac output.

Conditions

• Mitral Valve Replacement

Interventions

Type	Name	Description
OTHER	Moderate-Intensity Interval Training (MIIT)	Duration: The program lasted 12 weeks with 3 sessions per week. Session Structure: * Each session lasted 20-45 minutes. * Exercise intensity was set at 50-70% of maximum heart rate (MHR). * Intervals consisted of 1-4 minutes of moderate-intensity exercise, followed by shorter rest periods of 1-2 minutes. Exercise Type: * Alternating aerobic activities targeting both upper and lower body, such as treadmill and walking. * A warm-up (5-10 minutes) and cool-down (5-10 minutes) with light stretching and low-intensity walking were included.
OTHER	Moderate-Intensity Continuous Training (MICT)	Duration: The program lasted 12 weeks with 3 sessions per week. Session Structure: * Each session lasted 30-60 minutes at a steady moderate intensity. * Exercise intensity was maintained at 50-70% of MHR without interruptions. Exercise Type: * Continuous aerobic activity, such as walking on a treadmill. * A warm-up (5-10 minutes) and cool-down (5-10 minutes) were included.

Timeline

• Start date: 2024-02-10
• Primary completion: 2025-01-05
• Completion: 2025-01-05
• First posted: 2026-02-27
• Last updated: 2026-02-27

Locations

1 site across 1 country: Pakistan