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Enrolling By InvitationNCT07436689

Long-Term Open-Label Extension Study of Oral Levosimendan

A Multicenter, Open-Label, Long-Term Extension Study for Oral Levosimendan (TNX-103)

Status
Enrolling By Invitation
Phase
Phase 3
Study type
Interventional
Enrollment
800 (estimated)
Sponsor
Tenax Therapeutics, Inc. · Industry
Sex
All
Age
Healthy volunteers
Not accepted

Summary

The purpose of this study is to provide continued access to treatment with oral levosimendan (TNX-103) and to describe the safety of continued use of TNX-103 in participants with pulmonary hypertension with heart failure with preserved left ventricular ejection fraction (PH-HFpEF) who received TNX-103 in a parent study.

Conditions

Interventions

TypeNameDescription
DRUGTNX-103Open-label oral levosimendan 1-3mg

Timeline

Start date
2026-03-13
Primary completion
2029-03-01
Completion
2029-03-01
First posted
2026-02-27
Last updated
2026-03-19

Locations

5 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT07436689. Inclusion in this directory is not an endorsement.

Long-Term Open-Label Extension Study of Oral Levosimendan (NCT07436689) · Clinical Trials Directory