NCT07435168

CHEST-CA: Study of Chest Pain and Hidden Cardiac Amyloidosis

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: Rigshospitalet, Denmark · Academic / Other
• Sex: Male
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

The objective of this observational, prospective study is to determine the prevalence of Cardiac Amyloidosis (CA) in males over the age of 65 who experience chest pain but show no signs of coronary artery disease (CAD). Prior to inclusion, all patients will have undergone a CT coronary angiogram or an Rb-PET scan to rule out the possibility of CAD. Participants will be subject to several examinations, including blood tests, urine samples, ECG, echocardiography, and bone scintigraphy. An endomyocardial biopsy may be conducted if necessary.

Conditions

• Cardiac Amyloidosis
• Chest Pain

Interventions

Type	Name	Description
OTHER	Screening thourgh examinations including bonescintigraphy	Clinical examination, blood samples, echo, bone scintigraphy

Timeline

• Start date: 2024-04-01
• Primary completion: 2027-04-01
• Completion: 2027-04-01
• First posted: 2026-02-27
• Last updated: 2026-02-27

Locations

1 site across 1 country: Denmark