NCT07433894

Scoliosis and Functional Outcomes in Children With Juvenile Idiopathic Arthritis

Comprehensive Evaluation of Scoliosis and Its Association With Functional Status, Postural Alignment, and Disease Activity in Children With Juvenile Idiopathic Arthritis

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Istanbul University · Academic / Other
• Sex: All
• Age: 8 Years – 18 Years
• Healthy volunteers: Accepted

Summary

Juvenile idiopathic arthritis (JIA) is a chronic inflammatory disease that may affect musculoskeletal development and posture in children. Spinal involvement, including scoliosis, is not routinely evaluated in clinical practice despite its potential impact on functional status and quality of life. This cross-sectional study aims to assess the presence of scoliosis in children with JIA and to investigate its association with functional status, postural alignment, and disease activity. Clinical and functional parameters will be analyzed to better understand the impact of spinal deformities in this population.

Detailed description

Juvenile idiopathic arthritis (JIA) is a chronic inflammatory disease that may negatively affect musculoskeletal development, posture, and overall physical function in children. Although peripheral joint involvement is well characterized, axial and postural abnormalities, including scoliosis, are not routinely assessed during follow-up despite their potential clinical significance. This cross-sectional study aims to evaluate the presence of scoliosis in children with JIA and to investigate its relationship with disease activity, functional status, pain, and postural alignment. Comprehensive clinical assessments, including physical examination, disease activity scores, and functional evaluation tools, will be performed. Where applicable, postural analysis and imaging findings will also be considered. By identifying the frequency and clinical impact of scoliosis in JIA, this study seeks to improve awareness of spinal involvement and to provide a basis for early recognition and multidisciplinary management strategies, including targeted physiotherapy interventions.

Conditions

• Scoliosis

Timeline

• Start date: 2026-04-01
• Primary completion: 2026-06-01
• Completion: 2026-07-01
• First posted: 2026-02-25
• Last updated: 2026-02-27