NCT07433816

Antimicrobial Photodynamic Therapy Or Lingual Scraper Associated With Periodontal Treatment In The Reduction Of Halitosis.

Toluidin Blue Orto-Mediated Antimicrobial Photodynamic Therapy Or Lingual Scraper Associated With Periodontal Treatment In The Reduction Of Halitosis.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 48 (actual)
• Sponsor: Medical University of Silesia · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to compare the effectiveness of two methods of treating bad breath. Patients are enrolled in the study based on an objective test using the Oral Chroma Device, which measures the concentration of volatile sulfur compounds in exhaled air, which are responsible for bad breath. Before the test begins, a sample will also be taken from the tongue to determine the total number of microorganisms. Patients are then randomly assigned to two groups. Control group: Cleaning the tongue with a tongue scraper and rinsing the mouth with an antiseptic mouthwash. Intervention group: Cleaning the tongue with a tongue scraper and antibacterial laser therapy on the tongue. Then, all study participants will undergo a procedure to clean tartar from all their teeth. Questions to be answered by the study: Will there be a decrease in the concentration of volatile sulfur compounds in exhaled air after treatment? Will the treatment results obtained after laser therapy be better compared to the classic method of treating bad breath? Cleaning procedures within the tongue will be performed at the beginning, then repeated after one week, two weeks, and 3 months from the baseline. After each stage, the concentration of substances in exhaled air that are responsible for bad breath will be measured. Samples will be taken from the tongue to determine the total number of microorganisms before the first tongue cleaning, and then after 2 weeks from the intervention.

Conditions

• Halitosis
• Halitoses
• Fetor Oris
• Oral Malodor

Interventions

Type	Name	Description
PROCEDURE	Tongue scraper and oral rinse treatment	The procedure involves treating the tongue with a tongue scraper and rinsing the mouth with a chlorhexidine solution.
PROCEDURE	Tongue scraper and aPDT (photodynamic therapy)	The procedure involves treatment with a tongue scraper and photodynamic therapy with toluidine blue using a diode laser.
PROCEDURE	full mouth scaling	removal of tartar deposits within both dental arches

Timeline

• Start date: 2025-06-20
• Primary completion: 2025-10-30
• Completion: 2025-12-30
• First posted: 2026-02-25
• Last updated: 2026-03-05

Locations

1 site across 1 country: Poland