NCT07433465

Early Pregnancy Serum Ferritin Levels as a Predictor for Gestational Diabetes Mellitus

High Serum Ferritin Early in Pregnancy May Predict the Development of Gestational Diabetes Later.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 556 (actual)
• Sponsor: Zagazig University · Other Government
• Sex: Female
• Age: 21 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

This prospective study evaluates a target population of pregnant women at the time of pregnancy diagnosis to investigate the predictive value of serum ferritin (SF) levels for the later development of gestational diabetes mellitus (GDM). The intervention involves measuring early-pregnancy SF, transferrin, and hemoglobin levels, alongside HbA1c, and comparing these biomarkers between women who later develop GDM and those who remain normoglycemic. The primary outcome is to assess the success rate of this diagnostic regimen in identifying high-risk individuals, aiming to establish SF as a valuable early biomarker for GDM to enable timely interventions.

Conditions

• Diabetes Mellitus

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Glycemic Markers	Fasting blood glucose (FBG), 2-h Post postprandial blood glucose (PPBG), HbA1c, and Fasting Serum Insulin (FSI).

Timeline

• Start date: 2022-12-05
• Primary completion: 2024-12-07
• Completion: 2025-10-10
• First posted: 2026-02-25
• Last updated: 2026-02-25

Locations

1 site across 1 country: Egypt