NCT07432256

Parasternal Block Added to Serratus Anterior Plane Block in Breast Reduction Surgery

The Effect of Adding a Parasternal Intercostal Plane Block to a Serratus Anterior Plane Block on Postoperative Opioid Consumption in Breast Reduction Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (actual)
• Sponsor: Zonguldak Bulent Ecevit University · Academic / Other
• Sex: Female
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate the effect of adding a Superficial Parasternal Intercostal Plane Block (PIPB) to the Serratus Anterior Plane Block (SAPB) on postoperative pain control in patients undergoing breast reduction surgery under general anesthesia. Effective postoperative analgesia is essential to reduce opioid consumption and improve recovery. All patients will receive standard general anesthesia. Patients will be allocated into three groups: a control group receiving no regional block, a group receiving SAPB alone, and a group receiving SAPB combined with PIPB. The primary outcome of the study is total opioid consumption within the first 24 hours after surgery. Secondary outcomes include postoperative pain scores, Quality of Recovery-15 (QoR-15) scores, and intraoperative remifentanil consumption. The study aims to determine whether SAPB reduces postoperative opioid requirements compared to no block, and whether adding PIPB provides additional analgesic benefit by blocking the anterior cutaneous branches of the intercostal nerves. The findings may contribute to improving multimodal analgesia strategies in breast surgery.

Conditions

• Breast Reduction
• Postoperative Pain
• Opioid Consumption

Interventions

Type	Name	Description
PROCEDURE	Serratus Anterior Plane Block (SAPB)	injection local anesthetic between 5th rib and serratus anterior muscle
PROCEDURE	Serratus Anterior Plane Block (SAPB) and parasternal intercostal plane block	both injection local anesthetic between 5th rib and serratus anterior muscle at midaxillary line and between 4th costal cartilage and pectoralis major muscle at next to the sternum

Timeline

• Start date: 2024-05-01
• Primary completion: 2025-08-25
• Completion: 2025-12-01
• First posted: 2026-02-25
• Last updated: 2026-02-25

Locations

1 site across 1 country: Turkey (Türkiye)