NCT07429318

Efficacy and Survival Analysis of Perioperative Treatment of Locally Advanced Gastric or Gastroesophageal Junction Cancer

Efficacy and Survival Prognosis Analysis of Perioperative Treatment of Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 300 (estimated)
• Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

This study is a single-center, retrospective cohort study. The purpose is to evaluate different perioperative treatment options on the efficacy and survival prognosis of locally advanced GC/GEJC, clarify whether the tumor regression grade can influence survival of patients using neoadjuvant therapy. Moreover, we aim to explore the clinical and pathological characteristics that will affect the long-term survival benefit of patients who underwent perioperative treatment.

Conditions

• Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma

Interventions

Type	Name	Description
PROCEDURE	Chemo only	Patients who only used chemotherapy during neodajuvant treatment period
PROCEDURE	Immunochemotherapy	Patients who used immunotherapy combined with chemotherapy during neodajuvant treatment period

Timeline

• Start date: 2026-01-01
• Primary completion: 2026-06-30
• Completion: 2026-12-31
• First posted: 2026-02-24
• Last updated: 2026-02-24

Locations

1 site across 1 country: China