NCT07429149

Radiographic and Clinical Evaluations of Mandibular Implant-Supported Overdentures Supported by Conventional and Zirconia CAD/CAM Bars: A Randomized Clinical Trial

Evaluation Of Mandibular Implant-Supported Overdenture: A Comparative Study of Conventional Bar Versus Zirconia CAD/CAM Bars

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Sara Mohamed Fakhry Meligy Mohamed · Academic / Other
• Sex: Male
• Age: 50 Years – 60 Years
• Healthy volunteers: Accepted

Summary

This randomized clinical trial aimed to evaluate the radiographic and clinical evaluations of mandibular implant-supported overdentures supported d by two different bar materials。 Completely edentulous patients received two implants in the mandibular canine region and were rehabilitated with overdentures supported by a conventional cobalt-chromium bar and a zirconia CAD/CAM bar。 Radiographic marginal bone loss around implants, crestal bone height changes posteriorly and clinical peri-implant parameters were assessed at baseline,6 months, and 12 months to compare the performance of both bar materials。

Detailed description

This randomized clinical trial was conducted to compare the radiographic and clinical outcomes of mandibular implant-supported overdentures supported by conventional cobalt-chromium bars and zirconia CAD/CAM bars。 Eligible completely edentulous patients were selected according to predefined inclusion and exclusion criteria。 All participants received two endosseous dental implants placed in the mandibular canine regions following a standardized surgical protocol。 After a healing period, patients were randomly allocated into two groups。 In the first group, overdentures were supported by using a conventional cast cobalt-chromium bar, while in the second group, overdentures were supported by using a zirconia CAD/CAM-fabricated bar。 Radiographic evaluations of marginal bone loss around implants and crestal bone height changes posteriorly were performed using cone beam computed tomography and clinical peri-implant parameters, including pocket depth, plaque index, bleeding index, and mobility were evaluated at baseline,6 months and after 12 months。 The primary outcome of this study was the evaluation of radiographic marginal bone loss around implants and crestal bone height changes posteriorly, while secondary outcomes included peri-implant soft tissue health parameters。 The collected data were statistically analysed to compare bone stability and clinical performance associated with the two bar materials over the observation period。

Conditions

• Edentulous Mandible

Interventions

Type	Name	Description
DEVICE	Cobalt-Chromium Bar Attachment	A conventional cast cobalt-chromium bar used to retain a mandibular implant-supported overdenture
DEVICE	Zirconia CAD/CAM Bar Attachment	A zirconia CAD/CAM-fabricated bar used to retain a mandibular implant-supported overdenture

Timeline

• Start date: 2022-07-18
• Primary completion: 2025-06-17
• Completion: 2025-06-19
• First posted: 2026-02-24
• Last updated: 2026-02-24

Locations

1 site across 1 country: Egypt