NCT07426211

Impact of Shift Work on Glucose and Lipid Metabolism of Hospital Workers

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 48 (estimated)
• Sponsor: Olga Ramich (formerly Pivovarova) · Academic / Other
• Sex: All
• Age: 18 Years – 67 Years
• Healthy volunteers: Accepted

Summary

The aim of the study is to evaluate circadian glucose, activity and dietary rhythms, as well as metabolic and cardiovascular risk associated with night shift work, sleep quality and well-being in a cohort of hospital staff, comparing employees with night shifts to employees without night shifts.

Detailed description

The parallel-arm study consists of group A of employees working night shifts and group B of employees not working night shifts. After a pre-screening and an inclusion examination, both groups attend their first visit after at least two day shifts before the start of their two-week observation phase. During the visit, anthropometric measurements are conducted, blood and hair samples are collected, and questionnaires are completed and handed out. During the observation period, the 24-hour activity and glucose rhythms of the study participants are measured and the food intake is documented. After an observation phase, group A attends a second visit after at least two night shifts, including blood and hair sample collection.

Conditions

• Chronodisruption
• Shift Work Disorder
• Glucose and Lipid Metabolism

Timeline

• Start date: 2026-03-01
• Primary completion: 2027-01-01
• Completion: 2028-01-01
• First posted: 2026-02-23
• Last updated: 2026-04-01

Locations

1 site across 1 country: Germany