NCT07425288

Contralateral Effects of Unilateral Isokinetic vs. Single-Leg Squat Training in Sedentary Women

Contralateral Effects of Unilateral Isokinetic vs. Single-Leg Squat Training on Strength, Proprioception, and Muscle Thickness in Sedentary Women: A Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 47 (actual)
• Sponsor: Cagatay Muslum Gokdogan · Academic / Other
• Sex: Female
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

This randomized controlled trial aims to investigate the contralateral effects of unilateral training in sedentary women. Specifically, the study compares unilateral isokinetic training and single-leg squat training to determine their effects on strength, proprioception, and muscle thickness in both the trained and untrained lower extremities. Participants will be randomly assigned to one of the training groups. The intervention will be applied to one lower limb only. Strength, proprioception, and muscle thickness will be assessed before and after the intervention period. The primary objective is to evaluate whether unilateral training induces cross-education effects in the contralateral limb. The findings of this study may contribute to rehabilitation strategies by clarifying the potential benefits of unilateral exercise programs for improving neuromuscular performance and muscle morphology in sedentary individuals.

Conditions

• Muscle Strength
• Proprioception

Interventions

Type	Name	Description
BEHAVIORAL	Unilateral Isokinetic Training	Unilateral isokinetic strength training will be applied to one lower extremity using an isokinetic dynamometer. The training program will be performed according to the study protocol. The contralateral limb will not receive any direct intervention.
BEHAVIORAL	Unilateral Single-Leg Squat Training	Participants will perform unilateral single-leg squat exercises on one lower extremity according to the study protocol. The opposite limb will not receive any direct training.

Timeline

• Start date: 2023-11-15
• Primary completion: 2024-04-10
• Completion: 2024-05-22
• First posted: 2026-02-20
• Last updated: 2026-02-20

Locations

1 site across 1 country: Turkey (Türkiye)