Trials / Recruiting
RecruitingNCT07422792
Anabolic Response To Intravenous Amino Acids In Chronic Intestinal Failure Patients
Anabolic Response To Protein And Assessment Of Metabolic Phenotype In Patients With Home Parenteral Nutrition And Chronic Intestinal Failure
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- Sponsor
- Institute of Oncology Ljubljana · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to gain insight into the actual protein requirements of patients with chronic intestinal failure (CIF) receiving home parenteral nutrition, which could improve clinical management of these patients. Based on collected data on protein kinetics, the study aims to further refine and personalize nutritional mixtures in patients with CIF. Additional aims include assessment of short-chain fatty acid metabolism and evaluation of gut microbiota function in patients with CIF.
Detailed description
This prospective cohort study evaluates anabolic response to intravenous amino acid administration and metabolic phenotype in patients with chronic intestinal failure (CIF) receiving home parenteral nutrition. The study aims to improve therapy of CIF patients by providing new insights into metabolism and anabolic response. Protein kinetics will be assessed to better define protein requirements and to support optimization and personalization of parenteral nutrition mixtures. The study will also assess short-chain fatty acid metabolism and provide insight into gut microbiota function in CIF patients.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Intravenous Amino Acids | Intravenous amino acid administration to assess anabolic response and protein kinetics in patients with chronic intestinal failure receiving home parenteral nutrition |
Timeline
- Start date
- 2022-04-01
- Primary completion
- 2024-03-31
- Completion
- 2027-12-31
- First posted
- 2026-02-20
- Last updated
- 2026-02-20
Locations
1 site across 1 country: Slovenia
Source: ClinicalTrials.gov record NCT07422792. Inclusion in this directory is not an endorsement.