Clinical Trials Directory

Trials / Completed

CompletedNCT07421635

Post-pyloric Feeding and Feeding Intolerance in ARDS Patients Receiving Prone Position Ventilation

Post-pyloric Feeding and Feeding Intolerance in ARDS Patients Undergoing Prone Position Ventilation: a Single-center, Retrospective Study

Status
Completed
Phase
Study type
Observational
Enrollment
319 (actual)
Sponsor
Southeast University, China · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Evidence remains limited regarding the optimal enteral nutrition (EN) route for acute respiratory distress syndrome (ARDS) patients undergoing prone positioning. This study aimed to explore the association of post-pyloric feeding with feeding intolerance (FI), specifically in that population.

Detailed description

This single-center retrospective study included adult patients with ARDS who received prone position ventilation at Zhongda Hospital, Southeast University, between July 30, 2016, and April 30, 2024. The primary outcome was the incidence of FI, defined as the failure to achieve an enteral energy intake of 17.5 kcal/kg/day within 72 hours of initiating EN. The statistical approaches utilized included multivariate regression, inverse probability weighting model, and marginal structural cox model to ensure the robustness of our findings. Subgroup analyses were also performed.

Conditions

Timeline

Start date
2016-07-30
Primary completion
2024-04-30
Completion
2024-12-30
First posted
2026-02-19
Last updated
2026-03-30

Source: ClinicalTrials.gov record NCT07421635. Inclusion in this directory is not an endorsement.