NCT07416214

Probiotics in Alleviating Microplastic-Induced Obesity

Probiotics in Alleviating Microplastic-Induced Obesity: A Randomized Double-Blind Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 96 (actual)
• Sponsor: Fudan University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The study attempts to conduct randomized double-blind controlled trials to understand whether daily exposure to microplastics (MPs) can cause potential impacts on human health, explore whether the intake of Lactiplantibacillus plantarum PD01 can alleviate potential obesity-related damages caused by MPs, and provide a scientific basis for the prevention and nutritional intervention of health hazards caused by MP exposure.

Conditions

• Intestinal Functional Disorder
• Inflammation

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Probiotics (Lactiplantibacillus plantarum PD01)	The probiotic supplement includes 0.2g Lactiplantibacillus plantarum FABYIO PD01 (containing 10 billion CFU) and 1.8g Fructooligosaccharides.
DIETARY_SUPPLEMENT	Placebo	The placebo includes 2.0g Fructooligosaccharides with an indistinguishable appearance and texture.

Timeline

• Start date: 2025-11-30
• Primary completion: 2026-01-12
• Completion: 2026-02-10
• First posted: 2026-02-18
• Last updated: 2026-02-25

Locations

1 site across 1 country: China