NCT07415616

Cold vs Warm Enteral Feeding and Gastric Emptying in Adult ICU Patients

Effect of Cold and Warm Enteral Feeding on Gastric Emptying in Adult Intensive Care Patients: A Cross-Over Study

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (estimated)
• Sponsor: Bursa Yuksek Ihtisas Training and Research Hospital · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In critically ill patients receiving enteral nutrition in the intensive care unit, the functional capacity of the gastrointestinal system can be significantly influenced by the mode of nutritional support. The temperature of enteral feeding may exert potential effects on gastric emptying, intestinal motility, and nutrient absorption. However, the existing literature on the impact of feeding temperature is limited, and randomized or cross-over controlled studies directly comparing warm and cold enteral feeding are scarce. This study aims to systematically evaluate the effects of enteral feeding temperature on feeding tolerance (vomiting and aspiration), gastric emptying rate (gastric residual volume), and the incidence of diarrhea, thereby providing evidence to inform clinical practice.

Conditions

• Gastric Emptying
• Enteral Nutrition (Food for Special Medical Purposes)

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	enteral nutrition	Cold enteral feeding (24-25 degree), warm enteral feeding (36-37 degree)
DIETARY_SUPPLEMENT	enteral nutrition	cold enteral nutrition

Timeline

• Start date: 2025-09-01
• Primary completion: 2026-05-01
• Completion: 2026-08-01
• First posted: 2026-02-17
• Last updated: 2026-02-18

Locations

1 site across 1 country: Turkey (Türkiye)