NCT07413796

Comparison of Skin Closure Techniques in Oncological Neurosurgical Procedures: Intradermal Running Suture Versus Transdermal Interrupted Sutures

Prospective Randomized Controlled Trial of Skin Closure Techniques in Oncological Cranial Neurosurgery: Interrupted Transdermal Sutures and Running Intradermal Suture.

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 382 (estimated)
• Sponsor: Medical University of Warsaw · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare two commonly used methods of closing the skin after surgery for an intracranial tumor. Skin closure is one of the most important steps in neurosurgical procedures, as it has a major influence on how well the wound heals. In patients with brain tumors, proper wound healing is especially important because it may affect how soon additional treatments, such as radiotherapy or chemotherapy, can be started. There are different ways to close the skin after surgery, including running sutures and interrupted sutures. Both methods are widely used and considered safe. However, in oncological neurosurgery, there is limited scientific evidence comparing their effects, and the choice of technique is often based on the surgeon's personal experience. In this study, investigators will compare skin closure using running absorbable sutures with interrupted non-absorbable sutures. Investigators will evaluate how well, depending on used suturing methods, the wound heals and how often wound-related complications occur, such as infection, separation of the wound edges, or leakage of cerebrospinal fluid. Investigators believe that the results of this study will help improve wound care in patients undergoing neurosurgical treatment for brain tumors and, as a result, may contribute to better recovery and overall quality of life.

Conditions

• Brain Tumor Adult
• Brain Tumor Benign
• Meningioma
• Glioma
• Glioblastoma

Interventions

Type	Name	Description
OTHER	Absorbable running intradermal suture	Absorbable sutures used to perform continuous/running intradermal skin closure.
OTHER	Non-absorbable interrupted transdermal suture	Non-absorbable sutures used to perform interrupted transdermal skin closure.

Timeline

• Start date: 2026-02-01
• Primary completion: 2028-02-01
• Completion: 2028-05-01
• First posted: 2026-02-17
• Last updated: 2026-03-27

Locations

1 site across 1 country: Poland