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Active Not RecruitingNCT07413679

Long-term Safety of Danicopan: IPIG Registry-based Cohort Study

An Observational Study to Assess Long-Term Safety of Danicopan Add-on Therapy in Patients With Paroxysmal Nocturnal Hemoglobinuria: Analysis of IPIG-Registry Data

Status
Active Not Recruiting
Phase
Study type
Observational
Enrollment
50 (estimated)
Sponsor
Alexion Pharmaceuticals, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a noninterventional cohort study using primary and secondary data from the International PNH Interest Group (IPIG) PNH registry. It is designed to characterize the long-term safety and tolerability of danicopan as add-on therapy to eculizumab or ravulizumab in adult participants with PNH.

Conditions

Interventions

TypeNameDescription
DRUGDanicopanParticipants will receive Danicopan as an add-on therapy.

Timeline

Start date
2025-08-18
Primary completion
2029-07-01
Completion
2029-07-01
First posted
2026-02-17
Last updated
2026-02-17

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT07413679. Inclusion in this directory is not an endorsement.