NCT07412652

Ozone Injection vs ESWT for Chronic Achilles Tendinopathy

Comparison of Ultrasound-Guided Local Ozone Injection and Extracorporeal Shock Wave Therapy in the Treatment of Chronic Achilles Tendinopathy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 63 (actual)
• Sponsor: Ankara City Hospital Bilkent · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This randomized controlled clinical trial compares ultrasound-guided local ozone injection, extracorporeal shock wave therapy, and conventional conservative treatment in patients with chronic Achilles tendinopathy. The study focuses on changes in pain, functional outcomes, and overall clinical improvement during the follow-up period.

Conditions

• Achilles Tendinopathy (AT)

Interventions

Type	Name	Description
OTHER	Ultrasound-Guided Local Ozone Injection	Ultrasound-guided local ozone injection is administered to the peritendinous region of the affected Achilles tendon under sterile conditions using a high-frequency linear transducer, according to a standardized treatment protocol.
DEVICE	Extracorporeal Shock Wave Therapy (ESWT)	Extracorporeal shock wave therapy is applied to the affected Achilles tendon according to a standardized treatment protocol.
OTHER	Conventional Conservative Treatment	Conventional conservative treatment consists of a standardized exercise program and activity modification.

Timeline

• Start date: 2025-05-02
• Primary completion: 2026-01-02
• Completion: 2026-01-15
• First posted: 2026-02-17
• Last updated: 2026-02-17

Locations

1 site across 1 country: Turkey (Türkiye)