NCT07411326

Does Intraoperative Application of Steroids Affect Early Outcomes in Patients Undergoing Endoscopic Lumbar Discectomy?

Does Intraoperative Application of Steroids Affect Early Outcomes in Patients Undergoing Endoscopic Lumbar Discectomy? - a Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (actual)
• Sponsor: Centro Hospitalar De São João, E.P.E. · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Prospective randomised trial assessing whether intraoperative application of steroids leads to better clinical outcomes in patients submitted to lumbar discectomy

Detailed description

Prospective randomised trial assessing whether intraoperative application of steroids leads to better clinical outcomes in patients submitted to lumbar discectomy A control group has hernia removal without preoperative application of dexamethasone whilst 2 mL of dexamethasone is applied to the intervention group after hernia removal The investigators evaluated outcomes through back and leg NRS 48h, 2 weeks, 1 month and 3 months after surgery and ODI at 1 and 3 months post op

Conditions

• Lumbar Radiculopathy
• Lumbar Herniated Disk

Interventions

Type	Name	Description
DRUG	Intervention Group	patients given intraoperative dexamethasone after hernia removal
OTHER	Control group (Normal Saline) (C)	patients given 2mL saline

Timeline

• Start date: 2022-09-10
• Primary completion: 2025-01-31
• Completion: 2025-01-31
• First posted: 2026-02-13
• Last updated: 2026-02-13

Locations

1 site across 1 country: Portugal