Trials / Not Yet Recruiting
Not Yet RecruitingNCT07410052
Microbiome-Targeted Enhancement of Neurocognition With Probiotics-Riboflavin Combination
Microbiome-Targeted Enhancement of Neurocognition With Probiotics-Riboflavin Combination (MENTOR)
- Status
- Not Yet Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 28 (estimated)
- Sponsor
- Center for Health Sciences, Serbia · Academic / Other
- Sex
- All
- Age
- 65 Years
- Healthy volunteers
- Accepted
Summary
This randomized, double-blind, placebo-controlled trial will evaluate whether 12 weeks of supplementation with the probiotic Lactobacillus rhamnosus GG combined with colon-delivered riboflavin will improve cognitive performance and brain physiology in older adults with memory complaints. The study will assess changes in cognitive outcomes together with neurophysiological markers to explore potential gut-brain axis mechanisms. Through its rigorous design, the trial will aim to determine whether targeted modulation of the intestinal environment can support brain function and cognitive health in aging.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Experimental 1 | Probiotic and riboflabin |
| DIETARY_SUPPLEMENT | Experimental 2 | Microcrystaline cellulose |
Timeline
- Start date
- 2026-04-15
- Primary completion
- 2027-07-15
- Completion
- 2027-08-15
- First posted
- 2026-02-13
- Last updated
- 2026-02-13
Source: ClinicalTrials.gov record NCT07410052. Inclusion in this directory is not an endorsement.