NCT07408895

Effect of Injectable Platelet Rich Derivatives on Orthodontic Canine Retraction

The Effect of Injectable Platelet Rich Derivatives on the Rate of Orthodontic Canine Retraction: A Split-Mouth Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 21 (actual)
• Sponsor: Sana'a University · Academic / Other
• Sex: All
• Age: 17 Years – 29 Years
• Healthy volunteers: Not accepted

Summary

This study evaluated the effect of injectable platelet-rich derivatives on the rate of orthodontic canine retraction. Patients requiring orthodontic canine retraction following premolar extraction were enrolled and divided into three groups using a split-mouth design. Injectable platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) were applied to compare their effects on the rate of tooth movement. The outcomes were assessed by measuring the amount of canine retraction over time.

Conditions

• Accelerate Tooth Movement

Interventions

Type	Name	Description
BIOLOGICAL	Platelet-Rich Plasma (PRP)	Autologous platelet-rich plasma prepared from the patient's own blood and injected locally at the experimental side to accelerate orthodontic canine retraction.
BIOLOGICAL	Platelet-Rich Fibrin (PRF)	Autologous platelet-rich fibrin prepared from the patient's own blood and injected locally to accelerate orthodontic canine retraction.

Timeline

• Start date: 2024-05-30
• Primary completion: 2024-09-05
• Completion: 2024-09-05
• First posted: 2026-02-13
• Last updated: 2026-02-13

Locations

1 site across 1 country: Yemen