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Not Yet RecruitingNCT07407010

BCMA/CD3 Bispecific Antibody as Bridging Therapy Before CAR-T Cell Infusion in RRMM

A Prospective Single-Arm, Single-Center Study of BCMA/CD3 Bispecific Antibody as Bridging Therapy Before CAR-T Cell Infusion in Relapsed or Refractory Multiple Myeloma

Status
Not Yet Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
10 (estimated)
Sponsor
Institute of Hematology & Blood Diseases Hospital, China · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study is a prospective, single-arm, multicenter trial designed to evaluate the hematologic response rate and safety of BCMA/CD3 bispecific antibody bridging therapy prior to CAR-T cell infusion in patients with relapsed/refractory multiple myeloma (RRMM).

Conditions

Interventions

TypeNameDescription
BIOLOGICALCM336 (BCMA/CD3 bispecific antibody)CM336 is a BCMA × CD3 bispecific antibody.

Timeline

Start date
2026-06-01
Primary completion
2027-05-31
Completion
2028-05-31
First posted
2026-02-12
Last updated
2026-02-12

Source: ClinicalTrials.gov record NCT07407010. Inclusion in this directory is not an endorsement.

BCMA/CD3 Bispecific Antibody as Bridging Therapy Before CAR-T Cell Infusion in RRMM (NCT07407010) · Clinical Trials Directory