NCT07405034

AI Driven EX Versus Conventional in PFPS

Artificial Intelligence Driven Exercises Versus Conventional Exercises Therapy for Patellofemoral

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

This study aims to investigate and compare the effect of AI driven exercises program versus the conventional exercises therapy program on pain, function and dynamic knee valgus angle in treatment of patellofemoral pain syndrome.This study is randomized controlled trial and includes 40 participants .These participants divided into 2 groups (A, B), each group will be assessed with 3 measurments (vas ,dynamic knee valgus, Kujala Anterior Knee Pain Scale) and each group will receive difeerent treatments. The individuals in group A(study group) will preceive AI driven exercises program while the individual in group B will receive conventional exercises therapy program. Participants in the both groups are prescribed a 6-week comprehensive exercises program (3 sessions per week) day after day and assessment procedure will be performed pre and post treatmeant .

Detailed description

PURPOSE : This study aims to investigate and compare the effect of AI driven exercises program versus the conventional exercises therapy program on pain, function and dynamic knee valgus angle in treatment of patellofemoral pain syndrome. BACKGROUND: Patellofemoral pain syndrome (PFPS) is one of the most common knee problems that disturb function and daily activities (Menek et al .,2025). Symptoms of PFPS can develop either slowly or abruptly, and pain tends to worsen with activities such as squatting, prolonged sitting, stair climbing, jumping, or running (Menek et al .,2025). PFPS affects approximately 25% of physically active individuals (Smith et al .,2018). Core training significantly improves pain and functional limitations in patients with PFP and improves lower extremity motor performance to some extent (Y. Wang et al., 2024). These results draw more attention to the importance of the core muscle performance for both prevention and rehabilitation of the knee injuries HYPOTHESES: A-Primary Hypotheses: This study will hypothesize that: 1. There will be no significant effect of AI driven exercises program on pain in treatment of patients PFPS . 2. There will be no significant effect of AI driven exercises program on function in treatment of patients PFPS . 3. There will be no significant differences of AI driven exercises program and on dynamic knee valgus in treatment of patients PFPS. 4. There will be no significant differences of conventional exercises therapy on pain in treatment of patients PFPS. 5. There will be no significant differences of conventional exercises therapy on function in treatment of patients PFPS. 6. There will be no significant differences of conventional exercises therapy dynamic knee valgus in treatment of patients PFPS. RESEARCH QUESTION: This study will try to answer the following questions: This study will try to answer:What are the effects of of AI driven exercises program and the conventional exercises therapy program on pain, function and dynamic knee valgus angle in treatment of patellofemoral pain syndrome ?

Conditions

• Patello Femoral Pain Syndrome

Interventions

Type	Name	Description
OTHER	conventional exercises therapy program	The individual in group B will receive conventional exercises therapy program. Participants are prescribed a 6-week comprehensive exercises program (3 sessions per week) day after day and assessment procedure will be performed pre and post treatmeant
OTHER	Ai driven EX	The individuals in group A(study group) will preceive AI driven exercises program . Participants in the both groups are prescribed a 6-week comprehensive exercises program (3 sessions per week) day after day and assessment procedure will be performed pre and post treatmeant

Timeline

• Start date: 2026-02-26
• Primary completion: 2026-10-30
• Completion: 2027-01-01
• First posted: 2026-02-12
• Last updated: 2026-02-12

Locations

2 sites across 1 country: Egypt