NCT07401927

Preemptive Analgesia in Laparoscopic Hysterectomy

The Effects of Preemptive Analgesic Protocols on Perioperative Pain Management in Laparoscopic Hysterectomy: A Prospective Observational Study

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 70 (estimated)
• Sponsor: Giresun University · Academic / Other
• Sex: Female
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to evaluate the effects of ibuprofen and paracetamol administered for pre-emptive analgesia to patients undergoing laparoscopic hysterectomy on pain scores during the first 24 hours postoperatively, the amount of opioids consumed postoperatively, and adverse effects such as postoperative nausea and vomiting.

Detailed description

Patients who undergo laparoscopic hysterectomy surgery are administered certain treatment methods for postoperative analgesia. These applications are a routine part of the procedure. They are medically and ethically necessary. Postoperative analgesia applications are initiated during the intraoperative process and continued during the postoperative process. The analgesia protocol to be used is determined by the patient's characteristics and the anaesthetist's experience. Multimodal analgesia protocols are scientifically accepted methods. Preemptive analgesia, a method used for pain control that reduces the severity of pain caused by analgesics, delays the initial need for analgesia, and reduces the need for painkillers, is one of these protocols. This method, applied before surgical incision or tissue damage, covers a wide range, from first-line analgesics such as paracetamol and ibuprofen to opioids and peripheral and central blocks. The aim of this study is to evaluate the effects of ibuprofen and paracetamol administered for preemptive analgesia in patients undergoing laparoscopic hysterectomy on pain scores in the first 24 hours postoperatively, the amount of opioids consumed postoperatively, and adverse effects such as postoperative nausea and vomiting.

Conditions

• Postoperative Analgesia
• Laparoscopic Hysterectomy

Interventions

Type	Name	Description
DRUG	Ibuprofen	Administered as part of standard institutional anesthesia practice.
DRUG	Parasetamol	Administered as part of standard institutional anesthesia practice.

Timeline

• Start date: 2026-02-02
• Primary completion: 2026-04-01
• Completion: 2026-05-01
• First posted: 2026-02-11
• Last updated: 2026-02-11