NCT07399431

Theta Burst Stimulation in the Management of Methamphetamine Use Disorder in Indonesia

Effectiveness of Theta Burst Stimulation in the Management of Methamphetamine Use Disorder in Indonesia: A Randomized Controlled Trial as a National Model for Comprehensive Management

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: Indonesia University · Academic / Other
• Sex: All
• Age: 18 Years – 59 Years
• Healthy volunteers: Not accepted

Summary

Methamphetamine use disorder (MUD) remains a major public health concern in Indonesia, with limited effective treatment options and high relapse rates. Theta Burst Stimulation (TBS) has emerged as a promising adjunctive intervention for reducing craving and improving clinical outcomes. This trial aims to evaluate the efficacy and safety of TBS for MUD. A RCT of 20 subjects was conducted to evalute the efficacy and safety of TBS as an adjunctive treatment to CBT in managing MUD.

Conditions

• Methamphetamine Use Disorder
• Theta Burst Stimulation
• Transcranial Magnetic Stimulation

Interventions

Type	Name	Description
DEVICE	Theta Burst Stimulation	A randomized controlled trial (RCT) of 20 participants underwent TBS and CBT intervention for MUD.
BEHAVIORAL	Cognitive Behavioral Therapy	The cognitive behavioral therapy (CBT) for methamphetamine use disorder (MUD) was conducted in 12 sessions (1 session per day). We utilized the module adapted from the Indonesia Drug Addiction and Relapse Prevention Program (Indo-DARPP) for MUD. The CBT was delivered by trained psychiatrist in group CBT setting.

Timeline

• Start date: 2025-10-19
• Primary completion: 2025-11-03
• Completion: 2025-11-05
• First posted: 2026-02-10
• Last updated: 2026-02-10

Locations

1 site across 1 country: Indonesia