NCT07399210

Noninvasive Detection of Lung Nodule Malignancy Using cfDNA Fragmentomics

A Prospective Clinical Study Evaluating the Noninvasive Use of Circulating Cell-Free DNA Fragmentomics to Differentiate Benign and Malignant Lung Nodules, With Emphasis on Small Nodules.

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 240 (estimated)
• Sponsor: Baohui Han · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this observational study is to learn if cfDNA fragmentomics can noninvasively diagnose whether lung nodules are benign or malignant in adults with imaging-detected lung nodules.

Conditions

• Lung Cancer (Diagnosis)
• Fragmentomics

Interventions

Type	Name	Description
OTHER	This study did not include intervention between two cohorts	This study did not include intervention between two cohorts

Timeline

• Start date: 2024-08-21
• Primary completion: 2026-08-21
• Completion: 2026-08-21
• First posted: 2026-02-10
• Last updated: 2026-02-10

Locations

1 site across 1 country: China