NCT07397403

The Efficacy of Doxycycline Post Exposure Prophylaxis for Preventing STIs Among MSM in Bangkok, Thailand.

The Efficacy of Doxycycline Post Exposure Prophylaxis for Preventing Sexually Transmitted Diseases (Gonorrhea, Chlamydia, Syphilis) Among Men Who Have Sex With Men in Bangkok, Thailand.

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 400 (estimated)
• Sponsor: Bangrak STIs Center · Other Government
• Sex: Male
• Age: 18 Days – 60 Days
• Healthy volunteers: Accepted

Summary

The objective of this research is to evaluate the efficacy and safety of doxycycline in MSM for preventing sexually transmitted infections (gonorrhea, chlamydia, and syphilis) in Thailand Participation in this study will last approximately 12 weeks and will include 2-3 clinic visits, along with 10-11 follow-up phone contacts over a period of 11 weeks.

Conditions

• Syphilis Infection
• Gonorrhea
• Chlamydia

Interventions

Type	Name	Description
DRUG	Doxycycline (200mg/day)	Doxycycline 200 mg single dose after unprotected sex within 24-72 hours

Timeline

• Start date: 2025-10-06
• Primary completion: 2026-10-05
• Completion: 2027-05-31
• First posted: 2026-02-09
• Last updated: 2026-02-09

Locations

1 site across 1 country: Thailand