NCT07397312

A Pilot Study to Test the Efficacy of a Commercial Toothpaste (Cosmetic Product)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 28 (estimated)
• Sponsor: Periotrap Pharmaceuticals GmbH · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This clinical multi-center, controlled, study will be carried out in volunteers with every 3- to 6-months professional tooth cleaning during their non-treatment period between 2 re-calls of a supportive periodontitis therapy regime. The efficacy of domestic oral hygiene by using a commercial dentifrice will be determined. Besides regularly used ingredients such as NaF and cleaning bodies the dentifrice contains a novel compound, which may be beneficial for the protection of an eubiotic oral microbiome. During the 3-month study period, participants will brush with their allocated study product twice daily.

Conditions

• Periodontitis

Interventions

Type	Name	Description
OTHER	Toothpaste	brushing teeth with toothpaste twice a day for and refrain from mouth rinsing after spitting out

Timeline

• Start date: 2025-07-28
• Primary completion: 2026-07-31
• Completion: 2026-07-31
• First posted: 2026-02-09
• Last updated: 2026-02-09

Locations

3 sites across 1 country: Germany