NCT07394933

Guided Bone Regeneration Using Ti-Reinforced PTFE Membrane Vs. Khoury's Technique in Augmentation of Posterior Mandibular Defects

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: British University In Egypt · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The aim of the present clinical trial is to compare two different alveolar ridge bone augmentation techniques for mandibular horizontal bone defects.

Detailed description

Will using PTFE membrane with a mixture of xenograft and particulate autogenous bone result in bone gain similar to standard Khoury's bone shell technique?

Conditions

• Atrophic Ridge

Interventions

Type	Name	Description
PROCEDURE	Khoury's bone shell technique	Bone blocks will be harvested from the retromolar area after measuring of the size required and measuring of the donor site anatomy. Piezoelectric device will be used to perform the graft osteotomy. The block size should be slightly larger than the defect size. Sharp bony edges will be smoothened, and the donor defect will be packed with gelatin sponges. The bone block margins will be smoothened and separated into two thinner bone shells using titanium disk with copious saline irrigation. The blocks will be fixed into the recipient site buccally using at least two micro-screws leaving a gap to be filled with bone graft.
PROCEDURE	GBR using Ti-reinforced PTFE Membrane	A non-resorbable ti-enforced polytetrafluoroethylene (PTFE) membrane will be fixed with titanium screws on the lingual bone plate and on the buccal bone plate allowing for packing of particulate mix of bone graft (50% Xenograft: 50% Autogenous graft).

Timeline

• Start date: 2025-06-15
• Primary completion: 2025-10-15
• Completion: 2026-04-01
• First posted: 2026-02-06
• Last updated: 2026-02-18

Locations

1 site across 1 country: Egypt