Trials / Not Yet Recruiting
Not Yet RecruitingNCT07394413
Surgical Handling of Fertility-preserving Treatments for Cervical Adenocarcinomas
- Status
- Not Yet Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (estimated)
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Academic / Other
- Sex
- Female
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Despite a growing body of literature on the subject, there is still uncertainty regarding direct comparisons between different conservative surgical techniques for cervical adenocarcinomas. In particular, it remains unclear whether fertility-sparing surgery for cervical adenocarcinomas - characterized by skip lesions - can ensure optimal disease control while achieving adequate obstetric outcomes. For this reason, a systematic review and meta-analysis of the literature, along with an analysis of our center's data, is warranted. This approach will allow a critical, comparative evaluation of the efficacy of the different techniques (conization, simple trachelectomy, and radical trachelectomy) and the identification of prognostic factors to guide therapeutic choice.
Conditions
Timeline
- Start date
- 2026-02-01
- Primary completion
- 2027-02-01
- Completion
- 2027-02-01
- First posted
- 2026-02-06
- Last updated
- 2026-02-06
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT07394413. Inclusion in this directory is not an endorsement.